January 26, 2010
Dr. Elaine Mardis is co-director of The Genome Center at Washington University in St. Louis. As director of technology development, she leads the center’s efforts…
January 26, 2010
Researchers at St. Jude Children’s Research Hospital and the Washington University School of Medicine in St. Louis have launched the Pediatric Cancer Genome Project…
January 25, 2010
Two leading medical centers on Monday launched the largest effort to date to find all of the genetic mutations that cause childhood cancer.
January 25, 2010
Researchers plan to map all the genes in childhood tumours to identify mutations that give rise to the cancers.
The Genome Center at Washington University focuses on the large scale generation and analysis of DNA sequence. We play a leadership role in The Human Genome Project, constructing the clone map and contributing 25% of the finished sequence. To better understand the human genome sequence and to advance… (more)
The long-term goal of the "Genomics of AML" program project is to define all the DNA changes that occur in adult AML cells, and to define the importance of these mutations for disease susceptibility, initiation, progression, relapse, and resistance. The short-term goal is to define the most frequently occurring mutations that affect outcomes from treatment, since these are the ones most likely to have an impact on therapy. more
Strain CDC 4225-83 was isolated in 1983 in Maryland where it caused neonatal meningitis. The genome is being sequenced to 8X coverage, using plasmid and fosmid libraries, and will be finished to an error rate of less than 1 per 10,000 bases. more